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Abstract
Chromatographic modifications have been made in the tetracycline fluorescence test for gastric cancer designed to improve its reliability. In limited studies using these modified procedures, tetracycline fluorescence was identified in the gastric sediments of 10 (91 %) of 11 patients with cancer of the stomach. By contrast, tetracycline fluorescence was not found on paper chromatography in the gastric sediments of 62 subjects with either normal stomachs or various benign lesions of the stomach. These promising but preliminary results are reported to encourage trial of these methods in areas where gastric cancer is prevalent.