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Abstract
An improved peroral intubation method is described for the study of gastric secretion in the guinea-pig. Volume, pH, titratable acidity, and output were registered under basal conditions and after stimulation with pentagastrin and betazole in doses ranging from 0.1 to 1125 μg/kg/h and 0.1 to 225 mg/kg/h respectively. The method is particularly suited for long-term studies of certain pathological conditions of the gastric mucosa.