Trypsins In Human Pancreatic Juice–Their Distribution as Found in 34 Specimens. Two Human Pancreatic Trypsinogens

L. A. Robinson Dept. of Surgery, University of Washington, School of Medicine, Seattle, Washington, USA, Dept. of Pharmacology, Yonsei University Medical School, Seoul, Korea, and Universitat Berne, Klinik Fur Kinderkrankheiten. Berne, Switzerland

Won J. Kim Dept. of Surgery, University of Washington, School of Medicine, Seattle, Washington, USA, Dept. of Pharmacology, Yonsei University Medical School, Seoul, Korea, and Universitat Berne, Klinik Fur Kinderkrankheiten. Berne, Switzerland

T. T. White Dept. of Surgery, University of Washington, School of Medicine, Seattle, Washington, USA, Dept. of Pharmacology, Yonsei University Medical School, Seoul, Korea, and Universitat Berne, Klinik Fur Kinderkrankheiten. Berne, Switzerland

B. Hadorn Dept. of Surgery, University of Washington, School of Medicine, Seattle, Washington, USA, Dept. of Pharmacology, Yonsei University Medical School, Seoul, Korea, and Universitat Berne, Klinik Fur Kinderkrankheiten. Berne, Switzerland

Abstract

Trypsinogen I was found in 33 of 34 patient pancreatic juice specimens and trypsinogen II was found in 11 patients. Trypsinogen I was found in ten of the latter patients. The trypsinogen 1 band represented 13.4 ± 11.5 per cent of the total protein found in the juice, while trypsinogen II represented 1.4 ± 3.4 per cent. The isoelectric point of trypsinogen I was 7.0 and that of trypsinogen II was 4.7–5.0.

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Trypsins In Human Pancreatic Juice–Their Distribution as Found in 34 Specimens. Two Human Pancreatic Trypsinogens

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