Abstract
In two persons, brother and sister, with repeated melaena, aimed angiography revealed the presence of vessel malformation in the gastrointestinal tract evidencing hereditary haemorrhagic teleangiectasia, also called the Rendu-Osler-Weber disease. The anamnesis of the father of the patients was positive, angiography was not performed. The cause of the decrease in the frequency and intensity of bleeding in our patients could not be explained as yet.