Abstract
Lipoprotein disorders are associated with changes in the bile lipid composition, and gallstone disease has been reported to be common in hyperlipoproteinemic patients. To find out whether there is a significant correlation between hyperlipoproteinemia and gallstone disease, we compared the prevalence of hyperlipoproteinemia in a consecutive series of male gallstone patients with that in an age-matched consecutive series of gallstone-free patients. The gallstone patients were hyperlipoproteinemic in 43.5% as compared with 22.5% in the control patients. This difference was statistically significant. Prebetahyperlipoproteinemia (type IV) was the most common lipoprotein disorder in gallstone patients as well as in control patients.