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Original Article

Acute Cholestasis, Hepatic Failure, and Fatty Liver in the Alcoholic

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Pages 299-303 | Received 30 Oct 1977, Accepted 01 Dec 1977, Published online: 23 Feb 2010
 

Abstract

Three alcoholic patients are described who presented with acute cholestasis and liver cell failure. In each patient the liver biopsy showed severe fatty change with cholestasis, but without typical alcoholic hepatitis. There was no evidence of extra-hepatic biliary obstruction, although one patient had chronic pancreatitis. Two of the three patients died of hepatic failure, but the third recovered and has remained well while abstaining from alcohol.

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