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Scandinavian Journal of Gastroenterology Volume 14, 1979 - Issue 2
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Original Article

The Effect of Parietal Cell Vagotomy and Selective Vagotomy with Pyloroplasty on Iron Absorption

A Prospective Randomized Study

B. Magnusson Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
,
A. Faxén Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
,
Å. Cederblad Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
,
L. Rosander Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
,
J. Kewenter Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
&
L. Hallberg Dept. of Medicine II, Dept. of Surgery III, and Dept. of Radiation Physics, Sahlgren's Hospital. University of Gothenburg, Gothenburg. Sweden
Pages 177-182 | Received 28 Jun 1978, Accepted 20 Sep 1978, Published online: 23 Feb 2010
 
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Abstract

Iron absorption from a composite meal was studied in 37 male patients before and 1 year after parietal cell vagotomy (PCV) and selective vagotomy with pyloroplasty (SV + P) in a prospective randomized series. The ability to absorb dietary non-haem iron was studied by relating in each subject the food iron absorption to the absorption from a small dose of ferrous iron. which has been shown to be unaffected by gastric surgery. After both PCV and SV + P there was a malabsorption of food iron which was statistically significant in patients with increased iron requirements caused by phlebotomy. Malabsorption of food iron was less marked after PCV and SV + P than in patients after gastric resection, and it is concluded that there may be no need for a general prophylactic iron supplementation in patients operated on with PCV and SV + P.

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