Hepatitis B Virus Markers among Family Contacts of Asymptomatic HB_sAg Carriers

G. Hess Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

M. Born Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

H. Dormeyer Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

B. ZÖller Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

W. Arnold Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

J. Knolle Dept. of Internal Medicine, Klinikum Charlottenburg, Freie Universität Berlin, Berlin, Second Dept. of Internal Medicine, Johannes Gutenberg Universität, Mainz, and Dept. of Internal Medicine, Diakonissen Krankenhaus, Flensburg, West Germany

Abstract

A study was undertaken to establish the risk of family contacts of HB_sAg carriers acquiring a hepatitis B virus (HBV) infection. About one-third of all household contacts of asymptomatic HB_sAg carriers had signs of past or ongoing HBV infection. Family contacts of HB_sAg carriers with high numbers of circulating Dane particles were shown to have a higher risk of developing HBV infection than family contacts of HB_sAg carriers without serological evidence of HBV synthesis. The probability of acquiring HBV infection was not different between spouses, parents, children, and brothers and sisters, respectively of asymptomatic HB_sAg carriers.

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Hepatitis B Virus Markers among Family Contacts of Asymptomatic HB_sAg Carriers

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Hepatitis B Virus Markers among Family Contacts of Asymptomatic HBsAg Carriers

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Hepatitis B Virus Markers among Family Contacts of Asymptomatic HB_sAg Carriers