Effect of Deglycyrrhizinated Liquorice on Gastric Mucosal Damage by Aspirin

W. D. W. Rees Dept. of Gastroenterology, University Hospital of Wales, Health Park, Cardiff, Wales, and Dept. of Surgery, King's College Hospital Medical School, London, United Kingdom

J. Rhodes Dept. of Gastroenterology, University Hospital of Wales, Health Park, Cardiff, Wales, and Dept. of Surgery, King's College Hospital Medical School, London, United Kingdom

J. E. Wright Dept. of Gastroenterology, University Hospital of Wales, Health Park, Cardiff, Wales, and Dept. of Surgery, King's College Hospital Medical School, London, United Kingdom

I. F. Stamford Dept. of Gastroenterology, University Hospital of Wales, Health Park, Cardiff, Wales, and Dept. of Surgery, King's College Hospital Medical School, London, United Kingdom

A. Bennett Dept. of Gastroenterology, University Hospital of Wales, Health Park, Cardiff, Wales, and Dept. of Surgery, King's College Hospital Medical School, London, United Kingdom

Abstract

Gastric mucosal damage induced by giving 60 mg aspirin orally to rats was reduced by simultaneous administration of 100–500 mg deglycyrrhizinated liquorice. Human faecal blood loss induced by 975 mg aspirin orally three times a day was less when 350 mg deglycyrrhizinated liquorice was given with each dose of aspirin.

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Effect of Deglycyrrhizinated Liquorice on Gastric Mucosal Damage by Aspirin

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Effect of Deglycyrrhizinated Liquorice on Gastric Mucosal Damage by Aspirin

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