Cortisol and Pancreatic Secretion

Observations on Pure Pancreatic Juice

L. Gullo Dept. of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Bologna, and Division of Surgery, G. B. Morgagni Hospital, Forli, Italy

P. L. Costa Dept. of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Bologna, and Division of Surgery, G. B. Morgagni Hospital, Forli, Italy

R. Tessari Dept. of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Bologna, and Division of Surgery, G. B. Morgagni Hospital, Forli, Italy

G. Fontana Dept. of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Bologna, and Division of Surgery, G. B. Morgagni Hospital, Forli, Italy

Abstract

In view of the conflicting results in the literature, we undertook a study of the effects of intravenous administration of control on the external secretion of the pancreas. The study was carried out in five subjects with external transduodenal drainage of the main pancreatic duct, performed after biliary tract surgery. The intravenous injection of cortisol, 100 mg, during a constant intravenous infusion of secretin and cholecystokinin did not cause any significant change in pancreatic secretion. The results do not confirm previous findings in man indicating an inhibitory effect of glucocorticoids given intravenously on exocrine pancreatic secretion.

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Cortisol and Pancreatic Secretion

Observations on Pure Pancreatic Juice

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Cortisol and Pancreatic Secretion

Observations on Pure Pancreatic Juice

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