Abstract
Electrophoretic separation of serum alkaline phosphatase fractions and measurement of serum alkaline phosphatase and serum γ-glutamyltransferase were carried out in 82 consecutive patients with suspected hepatobiliary disease to investigate the usefulness of the three tests in distinguishing between parenchymatous hepatic disease and occlusive hepatobiliary disease. It was concluded that measurement of total serum alkaline phosphatase was superior to the two other tests.