Circadian Absorption of Vitamin B₁₂

A. Markiewicz Dept. of Gastroenterology and Dept. of Nuclear Medicine, Silesian School of Medicine, Katowice, Poland

T. Gomoluch Dept. of Gastroenterology and Dept. of Nuclear Medicine, Silesian School of Medicine, Katowice, Poland

E. Marek Dept. of Gastroenterology and Dept. of Nuclear Medicine, Silesian School of Medicine, Katowice, Poland

H. Bołdys Dept. of Gastroenterology and Dept. of Nuclear Medicine, Silesian School of Medicine, Katowice, Poland

Abstract

The effect of time of day on the vitamin B₁₂ absorption was studied in 10 human volunteers. A Schilling test was done with 37 kBq (1μCi) of ⁵⁷Co-labelled vitamin B₁₂ as an analysis of urinary radioactivity. Absorption at 1300 was significantly higher than that starting at 0700 (p < 0.001), at 1900 (p < 0.02), and at 0100 (p < 0.005).

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Circadian Absorption of Vitamin B₁₂