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Original Article

Effect of Jejunoileal Bypass Operation and Billroth II Resection on Postprandial Plasma Pancreatic Polypeptide Release

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Pages 613-617 | Received 16 Nov 1981, Accepted 08 Jan 1982, Published online: 19 Feb 2010
 

Abstract

In five jejunoileal bypass-operated subjects mean plasma pancreatic polypeptide (PP) values were significantly higher 15, 30, and 60 min after start of a meal 2 weeks postoperatively, and 15 min after start of a meal 6 weeks postoperatively, as compared with preoperative values. In a group of eight obese subjects, operated on with jejunoileal bypass 2-5 years ago, the postprandial plasma PP release tended to be higher than in an age-matched control group, the difference, however, being significant at 15 min only. On the other hand, the postprandial plasma PP release in a group of six Billroth-II-resected patients was almost identical to that seen in an age-matched control group. It appears as though neither the antrum nor the small intestine is a prerequisite for a normal PP response to a mixed liquid test meal.

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