Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 18, 1983 - Issue 8
Submit an article Journal homepage
6
Views
16
CrossRef citations to date
0
Altmetric
Original article

Studies of Peripheral Blood Lymphocytes in Crohn's Disease: Circulating Activated T Cells

F. Pallone Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
,
S. Montano Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
,
S. Fais Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
,
M. Boirivant Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
,
A. Signore Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
&
P. Pozzilli Depts. of Gastroenterology and Endocrinology, University of Rome, Rome, Italy
Pages 1003-1008 | Received 06 Oct 1982, Accepted 01 Feb 1983, Published online: 19 Feb 2010
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

Peripheral blood mononuclear cells have been investigated in 43 patients with Crohn's disease (CD) by means of a panel of 4 monoclonal antibodies (UCHT1, UCHT4, 4F2, 5E9). A decrease of total T cells (UCHT1+) (p < 0.01) and a slight increase of cytotoxic/suppressor T cells (UCHT4+) were observed. Evidence of T-cell activation, as shown by the highly significant increase of 4F2+ and 5E9+ cells, was also found. The latter finding lends support to the concept that cell-mediated immune phenomena are an important feature in CD.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.