The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment

J. Naesdal Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

T. Lind Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

J. Bergsåker-aspöy Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

T. Bernklev Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

P. G. Farup Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

R. Gillberg Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

L. Halvorsen Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

A. Kilander Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

S. Offergaard Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

A. Walan Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

K. A. Lloyd-Davies Dept. of Medicine, Centrals]ukehuset i Rogaland, Stavanger; Medical Dept., Astra Farmasøytiske A/S, Skårer; and Dept. of Medicine, Gjøvik Fylkessykehus, Gjøvik, Norway

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Abstract

We have studied the rate of healing of duodenal ulcers in 44 patients treated with omeprazole, 40 mg once daily for 4 weeks, with or without an 80-mg loading dose on day 1. Fourteen patients (32%) had healed by the end of the 1st week's treatment and a further 27 after a further week (giving a cumulative total of 93%). All patients (100%) had healed by the end of the treatment period. There was no significant difference in healing rate between the two treatment groups. Ulcer symptoms were relieved rapidly, and the drug was well tolerated.

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The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment

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The Rate of Healing of Duodenal Ulcers during Omeprazole Treatment

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