A Randomized Trial of Iohexol versus Amidotrizoate in Endoscopic Retrograde Pancreatography

A. Reimer Jensen Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

A. Malchow-Mosller Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

P. Matzen Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

J. E. Larsen Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

F. Mosller Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

J. Rikardt Andersen Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

E. Magid Depts. of Diagnostic Radiology and Medical Gastroenterology, Hvidovre Hospital, Hvidovre, and Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

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Abstract

To evaluate whether a low-osmolar contrast medium could decrease hyperamylasemia after endoscopic retrograde pancreatography, a prospective randomized double-blind trial of 54 consecutive patients with suspected pancreatic disease referred for endoscopic retrograde pancreatography was performed. The low-osmolar contrast medium iohexol and high-osmolar amidotrizoate were used. No statistically significant differences with regard to rise in pancreatic-type amylase, pain reaction, or diagnostic information were found. No case of acute pancreatitis was observed.

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A Randomized Trial of Iohexol versus Amidotrizoate in Endoscopic Retrograde Pancreatography

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A Randomized Trial of Iohexol versus Amidotrizoate in Endoscopic Retrograde Pancreatography

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