AIDS and the Gut

Abstract

The epidemiological, immunological and early virological observations on the acquired immune deficiency syndrome (AIDS) suggested that an agent was involved which was sexually, parenterally and perinatally transmitted and perhaps tropic for T helper lymphocytes. A new subgroup of human T lymphotropic retroviruses have been identified and seroepidemiological studies suggest that they are aetiologically related to AIDS. The syndrome is characterised by the development of tumours: such as Kaposi's sarcoma and non-Hodgkins lymphoma. with an aggressive clinical course and infection by a wide spectrum of opportunistic organisms, Both the tumours and the infections commonly involve the gut.