Malignancy in Crohn's Disease

N. Kvist Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

O. Jacobsen Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

P. Nørgaard Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

H. H. Ockelmann Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

H. K. Kvist Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

G. Schou Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

S. Jarnum Surgical Dept. C, and Division of Gastroenterology, Medical Dept. P, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Dept. of Theoretical Statistics, Copenhagen School of Economics and Business Administration, Copenhagen, Denmark; The Danish Cancer Registry, Copenhagen, Denmark

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Abstract

The incidence of cancer in Crohn's disease has been evaluated in 473 patients admitted to Rigshospitalet during the period 1 April 1964 to 1 January 1983. The patients' condition at the end of the survey, their survival, and the number and location of cancers were registered. During the survey period 23 cancers (4.9%) were found. Five were intestinal (1.1%) and were split evenly among the two sexes, whereas among 18 patients with extraintestinal cancers there was only 1 man. There was no increased risk of developing cancer inside the gastrointestinal tract compared with a background population matched for age, sex, and calendar time. Extraintestinal cancer in women was, however, significantly in excess.

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Malignancy in Crohn's Disease

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Malignancy in Crohn's Disease

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