Duodenal Output and Concentration of Lactoferrin in Chronic Pancreatitis: Correlation to Amylase Secretion and Duct Morphology

J. Hegnhøj Dept. of Internal Medicine and Dept. of Clinical Physiology, Hvidovre Hospital, Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

O. B. Schaffalitzky De Muckadell Dept. of Internal Medicine and Dept. of Clinical Physiology, Hvidovre Hospital, Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

J. B. Lauritzen Dept. of Internal Medicine and Dept. of Clinical Physiology, Hvidovre Hospital, Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

J. R. Andersen Dept. of Internal Medicine and Dept. of Clinical Physiology, Hvidovre Hospital, Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

E. Magid Dept. of Internal Medicine and Dept. of Clinical Physiology, Hvidovre Hospital, Dept. of Clinical Chemistry, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark

Abstract

To evaluate the clinical value of lactoferrin determination in duodenal contents in patients with chronic pancreatitis, three different studies were performed. No significant difference in meal stimulated output or secretion pattern was found between seven patients with chronic pancreatitis and six controls. After a meal test in 88 patients suspected for pancreatitis no correlation between concentration of lactoferrin and amylase was found. No correlation was found between degree of obstruction at endoscopic retrograde pancreaticography and duodenal concentration of lactoferrin. We conclude that the diagnostic value of lactoferrin determinations in chronic pancreatitis is doubtful.

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Duodenal Output and Concentration of Lactoferrin in Chronic Pancreatitis: Correlation to Amylase Secretion and Duct Morphology

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Duodenal Output and Concentration of Lactoferrin in Chronic Pancreatitis: Correlation to Amylase Secretion and Duct Morphology

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