Abstract
Short term studies of the prevention of bleedings from Paptic; have been reported by a number of authors following treatment with ± H2-receptor blockers, cimetidine (2-15), a combination of cimetidine and $ acid (16), cimetidine and somatostatin (17), cimetidine and sucralfate or $(18, 19, 20), cimetidine compared to antacid (21), and cimetidine $ antacid and pirenzepine (22). The H2-blocker rantitidine has been compare to-placebo (24, 25, 26). An uncontrolled study has been performed using $ (27), a controlled study with vasopressin (28) and with secretin versus $(28). In the studies with H2-receptor antagonists conflicting results have been obtained. No report has. been published concerning the effect ever $ days or weeks.