The Hemostatic Mechanism: The Role of Platelets in Physiology and Bleeding States

Abstract

The most recent information about platelets and their role in hemostasis is presented. The intimate cooperation between platelets, coagulation, and the vessel wall (the thrombohemorrhagic balance) is outlined. Clinical correlates (congenital and acquired bleeding states) to the various physiological stages and the possible effects on hemostasis of the unique acidic environment of the stomach are briefly discussed.

Key Words:

• Acquired
• aggregation
• bleeding
• congenital
• hemostasis
• pathology
• pH
• physiology
• platelets