![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
Gastric bile salt concentrations, the rates of bile salt reflux, gastric emptying, and gastric volume secretion were measured in 9 women with previous cholecystectomy and 13 unoperated female controls. The subjects were studied using a marker technique with gastric intubation both fasting and after gastric instillation of a mixed liquid meal. Cholecystectomy was without effect on gastric emptying and gastric-volume secretion. Cholecystectomized patients had increased bile salt reflux rates (1.4 ± 0.4 versus 0.6 ± 0.2 μmol/min) and gastric bile concentrations (1753 ± 266 versus 441 ± 114 μmol/l) in the fasting state, but lower rates (0.3 ± 0.3 versus 3.4 ± 0.9 μmol/min) and concentrations (131 ± 46 versus 496 ± 123 μmol/l) after feeding. These findings can be explained by the changes of bile flow into the duodenum induced by cholecystectomy.