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Original Article

Gallbladder Stones Classified by Chemical Analysis of Cholesterol Content Frederiksberg, 1987–1988

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Pages 720-724 | Received 17 Nov 1989, Accepted 31 Jan 1990, Published online: 08 Jul 2009
 

Abstract

Gallstones from 80 cholecystectomies and 81 autopsies were chemically analysed and showed a trend of decreasing cholesterol content with increasing age (p = 0.00009). The frequency of cholesterol stones (cholesterol content >70%) was higher in operated women (81%) than in operated men (33%) (p = 0.0006) and in the total autopsy material (42%). The study supports the theory that the predominance of gallstone disease in women is an effect of the preponderance of cholesterol stones. The accuracy of estimates of cholesterol content of gallstones from the appearance of the cut surface was low. When the chemical analysis was used as a key, only one in three was correct. There was a tendency to underestimate cholesterol content.

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