Risk of Gastric Cancer in Patients with Non-Surgically Treated Peptic Ulcer

S. Lee Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

M. Iida Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

T. Yao Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

S. Shindo Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

Y. Nose Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

K. Akazawa Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

H. Okabe Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

M. Fujishima Second Dept. of Internal Medicine, Kyushu University, Kanagawa, Japan; Dept. of Medical Informatics, Faculty of Medicine, Kyushu University, Kanagawa, Japan; First Dept. of Internal Medicine, School of Medicine, Fukuoka University, Karatsu Gastric Institute, Fukuoka, Karatsu; Dept. of Internal Medicine, School of Medicine, Kitasato University, Kanagawa, Japan

show all

Abstract

We followed up 2072 patients with unoperated gastric and duodenal ulcer, diagnosed from 1963 to 1975, and evaluated the risk of development of gastric cancer. During the follow-up period of 9–23 years 38 patients had a gastric cancer or died of gastric cancer. The number of gastric cancers in patients with duodenal ulcer (observed/ expected = 3:12) was statistically low (p < 0.01) compared with the number expected from the sex- and age-matched general population. On the other hand, the number of patients with gastric ulcer and the number of those with both gastric and duodenal ulcers was 29 and 6, neither of which differed significantly from the expected occurrence. These results suggest that in peptic ulcer patients the risk of developing gastric cancer is equal to or low compared with that of the general population.

Key Words:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Risk of Gastric Cancer in Patients with Non-Surgically Treated Peptic Ulcer

Information for

Open access

Opportunities

Help and information

Risk of Gastric Cancer in Patients with Non-Surgically Treated Peptic Ulcer

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature