15
Views
11
CrossRef citations to date
0
Altmetric
Original Article

Helicobacter pylori and Gastric Cancer

Pages 31-33 | Published online: 08 Jul 2009
 

Abstract

Epidemiological studies have consistently shown an association between infection with Helicobacter pylori and gastric cancer. The strongest evidence comes from three prospective studies that have shown the risk of gastric cancer to be increased by about fourfold in infected individuals. This raises the possibility of preventing a substantial number of gastric cancer cases by controlling H. pylori. Screening asymptomatic populations and eradicating the organism in those infected is the only treatment strategy currently available, but several questions remain to be answered before this can be recommended as a routine public health measure. Research into H. pylori has transformed understanding of the aetiology of gastric cancer, focusing attention on factors such as chronic inflammation, impaired host defence mechanisms and oxidative cell damage.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.