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Case Report

The entire genome sequence of hepatitis E virus genotype 3 isolated from a patient with neuralgic amyotrophy

, , , , &
Pages 395-400 | Received 22 Jul 2009, Accepted 17 Nov 2009, Published online: 26 Jan 2010
 

Abstract

We report the case of a Thai male patient with neuralgic amyotrophy, presenting with acute and severe pain in the upper extremities, followed by patchy muscle weakness, associated with hepatitis E virus (HEV) infection. The entire HEV genome was sequenced and subjected to phylogenetic analysis and found to be genotype 3. Data on the most common HEV genotypes circulating in Thailand are scarce. The origin of infection and the mode of HEV transmission in this patient remained inconclusive; however, this study provides essential baseline data as a reference for further genetic analysis of HEV.

Acknowledgements

The authors received financial support from the Center of Excellence in Clinical Virology Fund, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Commission on Higher Education, Ministry of Education and CU Centenary Academic Development Project.

Declaration of interest: No conflict of interest.

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