Mannose-resistant Haemagglutination by Campylobacter pylori

Levente Emödy Department of Medical Microbiology, University of Lund, Lund, Sweden; Department of Medical Microbiology, University of Pecs, Pecs, Hungary

Åsa Carlsson Department of Medical Microbiology, University of Lund, Lund, Sweden

Åsa Ljungh Department of Medical Microbiology, University of Lund, Lund, Sweden

Torkel Wadström Department of Medical Microbiology, University of Lund, Lund, Sweden

Abstract

10 Campylobacter pylori strains were screened for the presence of presumptive colonization factors by measuring cell surface hydrophobicity and haemagglutination. All 8 clinical isolates and 2 reference strains caused haemagglutination of rabbit, human and/or sheep erythrocytes in the presence of mannose. None of the strains expressed a hydrophobic cell surface. In preliminary experiments the haemagglutination could be inhibited with monosia-logangliosides suggesting that these strains express sialic acid specific haemagglutinin(s) which could be involved in colonization of mucosal surfaces.

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Related Research Data

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Source: Wiley

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