Exophthalmus in Chronic Renal Insufficiency

Abstract

The present results show that exophthalmus is a common symptom in chronic renal insufficiency. Thus, contrary to the norm, 19 (67%) of 28 clinically euthyroid, chronic dialysis patients displayed increased Hertel values. Tests of thyroid function in these patients indicated a reduced thyroxine-binding capacity of the serum protein and, in some cases, a stimulation of the thyroid gland. Possible causes of exophthalmus, such as a hyperthyroid metabolism due to the chronic renal insufficiency, or disturbed hypophysial secretion with production of an exophthalmus-producing factor (EPF) are discussed.