Abstract
Urea dialysance and ultrafiltration at constant blood flow has been compared in two-parallel-flow artificial kidneys—the A-G and R-P Haemodialysers. The urea dialysance was constant in both cells. At dialysate flows of between 450 and 800 ml/min the efficiency of the R-P Haemodialyser was the greatest. At an average dialysate flow of 602 ml/min the urea dialysance was 68 ml/min for the A-G Haemodialyser. At an average dialysate flow of 632 ml/min the urea dialysance was 86 ml/min with the R-P Haemodialyser. The ultrafiltration rate was found to be greater with the A-G Haemodialyser.
Membrane rupture was observed in the A-G Haemodialyser in 0.1% compared to 2.5% in the R-P Haemodialyser. Pyrogene reactions were not observed with either of the two units.
The application of either the A-G or R-P Haemodialysers could result in a possible saving in labour costs when dialysis is carried out in two shifts. There is also a reduced risk of infection.