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Abstract
A method is described for the evaluation of kidney damage after cold and warm ischemia. Rabbit kidneys were perfused with different perfusion fluids. Urines and perfusates were examined. Of the parameters investigated it was found that lactate dehydrogenase and potassium were the first to show signs of kidney damage. Suspect damage after 24 hours' cold ischemia and pronounced damage when 1 hour's warm ischemia was added to the cold ischemia could be observed. The present author considers that the method can be used in the clinical evaluation of the viability of a donor's kidney, provided that such a kidney is re-perfused prior to the transplantation and provided that the parameters investigated are considered. Nevertheless, a more sensitive in vitro test for viability is desired.