Studies on Burns Xiv. Plasma Renin Activity Correlated to Renal Function in Burned Patients

L. Božovi Burns Unit and the Departmetrts of Anaesthesiology, Clinical Physiology and General Surgery, the Urological Research Laboratory, Karolinsku sjukhuset, and King Gustaf V Research Institute, Stockholm, Sweden

J. Castenfors Burns Unit and the Departmetrts of Anaesthesiology, Clinical Physiology and General Surgery, the Urological Research Laboratory, Karolinsku sjukhuset, and King Gustaf V Research Institute, Stockholm, Sweden

J. Eklund Burns Unit and the Departmetrts of Anaesthesiology, Clinical Physiology and General Surgery, the Urological Research Laboratory, Karolinsku sjukhuset, and King Gustaf V Research Institute, Stockholm, Sweden

P.O Granberg Burns Unit and the Departmetrts of Anaesthesiology, Clinical Physiology and General Surgery, the Urological Research Laboratory, Karolinsku sjukhuset, and King Gustaf V Research Institute, Stockholm, Sweden

S.O Liljedahl Burns Unit and the Departmetrts of Anaesthesiology, Clinical Physiology and General Surgery, the Urological Research Laboratory, Karolinsku sjukhuset, and King Gustaf V Research Institute, Stockholm, Sweden

Abstract

Plasma renin activity (PRA), renal function, water and electrolyte balance were followed during the treatment of 18 patients with burn injuries. The burned area varied from 5 to 95% of the body surface area. Plasma renin activity was considerably increased during the initial 4 days after injury as well as during the 5 last days of life in the fatally injured 9 cases. Hypernatremia (hyperosmolality) was seen concomitantly with very high plasma renin activity. Increased sympathetic activity is supposed to be the main cause of the high levels of plasma renin activity.

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Studies on Burns Xiv. Plasma Renin Activity Correlated to Renal Function in Burned Patients

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Studies on Burns Xiv. Plasma Renin Activity Correlated to Renal Function in Burned Patients

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