Intracavitary Epodyl® for Multiple, Non-Invasive, Highly Differentiated Bladder Tumours

Abstract

Multiple, recurrent cancer of the bladder grade I-II (WHO), stage TI (UICC) was treated with regular intravesical instillation of ethoglucid (Epodyl®) in 39 patients. In ten of them cystitis necessitated withdrawal of the treatment. The therapeutic schedule could be followed in 29 cases, with eradication of the tumours in 27. Nine patients who continued the treatment on a prophylactic basis were still recurrence-free after 18–60 (mean 37) months. Myelosuppression did not occur, but cystitis was a serious problem that frequently jeopardized therapy.