The Urodynamic Patterns and Pathophysiology of the Canine Allotransplanted Upper Urinary Tract

Abstract

The urodynamic patterns of pelvic pressure, pelvic volume and frequency of ureteral peristalsis and the pathology of the upper urinary tract after renal allotransplantation were investigated in 41 dogs. The findings were compared with previous measurements of both normal and renally autotransplanted dogs. The urodynamic patterns of the allotransplants were unchanged and not influenced by variations of renal function or degree of rejection. Morphologic alterations of collagen infiltration in the smooth muscle tissue changed the viscoelastic behaviour of the system. Finally, the results support that myogenic impulses govern the urinary transport from the canine kidney to the bladder.