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Scandinavian Journal of Urology and Nephrology Volume 15, 1981 - Issue 1
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Original Article

Influence of Sympathetic Tonus and Plasma Noradrenaline on Urethral Pressure

J. NordlingUrological Laboratory, Urology Department H and the Departments of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Denmark
,
H. H. MeyhoffUrological Laboratory, Urology Department H and the Departments of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Denmark
&
N. J. ChristensenUrological Laboratory, Urology Department H and the Departments of Internal Medicine and Endocrinology, Herlev Hospital, University of Copenhagen, Denmark
Pages 1-6 | Received 15 Oct 1979, Published online: 15 Feb 2010
 
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Abstract

The relative influence of circulating noradrenalin and sympathetic tonus on urethral pressure was investigated by intravenous administration of noradrenalin and clonidine. Raising circulating noradrenalin concentrations by noradrenalin infusion had only a relatively minor effect on urethral pressure, indicating that urethral pressure is not controlled by circulating noradrenalin. Besides depression of sympathetic tonus and urethral pressure, clonidine reduced striated anal sphincter activity.

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