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Original Article

Evaluation of Renal Concentrating Ability with DDAVP and Pitressin

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Pages 69-71 | Received 15 Jun 1978, Published online: 15 Feb 2010
 

Abstract

This paper reports an attempt to develop a rapid test of the renal concentrating ability using a newly synthetized vasopressin analogue, DDAVP (1-desamino-8-D-arginine-vasopressin), which was given intravenously in a dose of 2 μg. Patients investigated for various endocrinological disorders were evaluated with both DDAVP and pitressin. There was a good correlation between the maximal urine osmolalities with both tests. Since DDAVP has fewer side effects and a more rapid onset of action it appears advantageous for investigations of renal concentrating ability.

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