The Outcome of 48 Renal Transplantations Immunosuppressed with Cyclosporine-A as Monotherapy

Birthe Lund HansenTissue Culture Laboratory, Department of Nephrology, University Hospital, 5000 Odense, Denmark

Inger HenriksenTissue Culture Laboratory, Department of Nephrology, University Hospital, 5000 Odense, Denmark

Nils RohrDepartment of Cardiovascular Surgery, University Hospital, 5000 Odense, Denmark

Valborg SvendsenDepartment of Cardiovascular Surgery, University Hospital, 5000 Odense, Denmark

Sven Arvid BirkelandTissue Culture Laboratory, Department of Nephrology, University Hospital, 5000 Odense, Denmark

Abstract

The course of 48 consecutive cadaveric renal transplantations immunosuppressed with Cyclosporine-A (CyA) as monotherapy in 3 different doses was retrospectively analysed. CyA doses were based on clinical observations. Overall one-year graft survival was 52% and for grafts immediate diuresing 82%. A dosage schedule of 12 mg CyA/kg/day seemed to secure graft function without any side effects to the patient.

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The Outcome of 48 Renal Transplantations Immunosuppressed with Cyclosporine-A as Monotherapy

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The Outcome of 48 Renal Transplantations Immunosuppressed with Cyclosporine-A as Monotherapy

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