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Original Article

Vasopressin and Cortisol Levels in Response to Glycine Infusion

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Pages 121-123 | Received 20 Jun 1990, Accepted 19 Aug 1990, Published online: 09 Jul 2009
 

Abstract

The plasma vasopressin and serum cortisol concentrations were recorded in 7 healthy volunteers receiving an intravenous infusion of II of isosmotic (2.2%) glycine solution during 20 min. The infusion elicited a significant increase in the plasma vasopressin level by a mean of 60% (SEM 13) above baseline level. The serum cortisol level increased only in the patient who developed signs of glycine toxicity. These results suggest that a glycine solution has water-retaining properties by stimulating the vasopressin secretion but usually not by increasing cortisol secretion.

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