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Scandinavian Journal of Urology and Nephrology Volume 30, 1996 - Issue 3
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Urology: Original experimental scientific reports

Urinary Glycosaminoglycan Excretion in Bladder Carcinoma

Özcan Atahan Urologic Clinics of TCDD Ankara Hospital, Faculty of Medicine, Gazi University, Ankara, Turkey
,
Önder Kayigil Urologic Clinics of TCDD Ankara Hospital, Faculty of Medicine, Gazi University, Ankara, Turkey
,
Nedret Hizel Departments of Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
,
Özlem Yavuz Departments of Biochemistry, Faculty of Medicine, Gazi University, Ankara, Turkey
&
Ahmet Metin Urologic Clinics of TCDD Ankara Hospital, Faculty of Medicine, Gazi University, Ankara, Turkey
Pages 173-177 | Received 20 Jun 1994, Accepted 15 Nov 1994, Published online: 15 Feb 2010
 
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Abstract

The urinary glycosaminoglycan (GAG) excretion in 35 patients with bladder cancer was significantly greater than that in 30 normal persons. In the cancer patients, the results were analysed according to tumour characteristics. Statistically significant differences were found, with increased GAG levels paralleling tumour size, multifocality, stage and grade. These preliminary data suggest that, parallel with established clinical parameters, measurement of urinary GAG excretion provides an indicator of repair of the bladder epithelium.

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