Prevalence of Autoantibodies Associated with Glomerulonephritis, Unaffected after Extracorporeal Shock Wave Lithotripsy for Renal Calculi, in a Three-year Follow-up

Abstract

Extracorporeal shock wave lithotripsy (ESWL) has become a useful tool in the treatment of renal calculi, but side effects may occur. Hitherto, two case reports have been published of an anti-glomerular basement membrane disease resulting in end-stage renal failure following ESWL treatment. In this prospective study of 59 consecutive patients undergoing ESWL for renal calculi, the prevalence of autoantibodies associated with glomerulonephritis was investigated before ESWL and at 3-year follow-up. The prevalences of antinuclear, anti-glomerular basement membrane, anti-neutrophil cytoplasmic and thyroid antibodies were found to be within the respective normal ranges prior to the first ESWL treatment and to be unaffected at follow-up.

Key Words:

• ANA
• ANCA
• anti-glornerular basement membrane
• autoantibodies
• ESWL
• renal calculi
• thyroid antibodies