![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
1. An intraperitoneal dose of [14C]isopropyl Oxitol is rapidly metabolized in the rat.
2. The major routes of excretion of radioactivity are the urine (73% dose) and in the expired air as [14C]carbon dioxide (14%).
3. The major urinary metabolites were characterized as isopropoxyacetic acid (30% of the urinary radioactivity), N-isopropoxyacetyl glycine (46%) and ethanediol (13%).
4. The metabolism of the compound in the dog is similar to that in the rat.