![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
1. Rabbits and rats dosed with cyclopentanone, cyclohexanone or cycloheptanone excrete traces of the corresponding 2-hydroxycycloalkylmercapturic acids.
2. In each case small amounts of a second sulphur-containing metabolite are excreted. Mass spectroscopic evidence suggests that these metabolites are the sulphate esters of 2-hydroxycycloalkylmercapturic acids.
3. Cyclopentyl and cycloheptyl glucuronides are the major metabolites of cyclopentanone and cycloheptanone in the rabbit.