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Xenobiotica
the fate of foreign compounds in biological systems
Volume 3, 1973 - Issue 7
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Research Article

The Place of Nuclear Magnetic Resonance Spectroscopy in Drug Metabolism Studies

Pages 451-471 | Received 01 Jan 1973, Published online: 14 Oct 2008
 

Abstract

1. An elementary introduction is provided to the theory of n.m.r. spectroscopy.

2. The different modes of operation are described with particular attention to the preparation and examination of small samples.

3. Examples are given of applications of n.m.r. spectroscopy to structure elucidation problems in drug metabolism studies. The particular value of n.m.r. in locating the positions of new hydroxyl groups is emphasized.

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