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Xenobiotica
the fate of foreign compounds in biological systems
Volume 6, 1976 - Issue 12
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Original Article

The Metabolism of Chlorpromazine in the Neonatal Guinea-Pig

S. C. Mitchell Biochemistry Department, University of Birmingham, Birmingham, B15 2TT, UK
&
R. H. Waring Biochemistry Department, University of Birmingham, Birmingham, B15 2TT, UK
Pages 763-768 | Received 20 Feb 1976, Published online: 30 Sep 2009
 
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Abstract

The metabolism of chlorpromazine in the neonatal guinea-pig has been studied. Maximal urinary excretions of sulphoxide occurred at 5 and 14 days, maximum excretion of both conjugated phenols and glucuronides at about 10 and 18 days.

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