Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 8
5
Views
5
CrossRef citations to date
0
Altmetric
Original Article

The Identification of Eight Hydroxylated Metabolites of Etidocaine by Chemical Ionization Mass Spectrometry

, &
Pages 509-513 | Received 12 Sep 1977, Published online: 30 Sep 2009
 

Abstract

1. Eight hydroxylated metabolites of etidocaine have been identified in urine of man by g.l.c.-chemical ionization mass spectrometry, using methane and a mixture of methane and deuterium oxide as reactant gases.

2. The metabolites identified were N-(2,6-dimethyl-3- and 4-hydroxyphenyl)-2-(N,N-ethylpropylamino)butyramides, N-(2,6-dimethyl-3- and 4-hydroxyphenyl)-2-aminobutyramides, N-(2,6-dimethyl-3- and 4-hydroxyphenyl) -2-(N-ethylamino)butyramides, and N-(2,6-dimethyl-3- and 4-hydroxyphenyl)-2-(N-propylamino)butyramides.

3. The eight metabolites represent about 10% of the oral dose of etidocaine.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.