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Xenobiotica
the fate of foreign compounds in biological systems
Volume 8, 1978 - Issue 1
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Research Article

Metabolism of Methylmercuric Chloride by the Gastro-Intestinal Flora of the Rat

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Pages 37-43 | Received 28 Jan 1977, Published online: 22 Sep 2008
 

Abstract

1. The contents of the caecum and small intestine of the rat metabolized methylmercuric chloride in vitro to a volatile product over a period of 3 to 4 days. The bacterial flora of the gut were responsible for the metabolism.

2. In the presence of caecal contents methylmercury was reduced to metallic mercury.

3. The contents of the small intestine metabolized methylmercuric chloride indirectly, as a result of prior synthesis of H2S to a volatile sulphur derivative of methylmercury.

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