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Abstract
1. Ethylestrenol incubated with a post-mitochondrial supernatant fraction of rat liver plus co-factors gives norethandrolone as the major metabolite.
2. A second (minor) metabolite was tentatively identified as 17α-ethyl-5ξ-estrane-3ξ,17β-diol.
3. A pathway is suggested for the metabolism of ethylestrenol in the rat.