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Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 3
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Research Article

The metabolism of pentachloromethylthiobenzene in germ-free and conventional rats

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Pages 173-178 | Received 19 Jun 1980, Published online: 22 Sep 2008
 

Abstract

1. Both germfree and conventional rats excreted over 80% of oral doses of pentachloromethylthio[14C]benzene in the faeces.

2. The faeces from germ-free rats contained mainly N-acetyl-S-(methylthiotetrachlorophenyl)cysteine.

3. The faeces from conventional rats contained bis-(methylthio)tetrachlorobenzene and non-extractable residues in about equal amounts.

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