Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 11, 1981 - Issue 3
Submit an article Journal homepage
10
Views
6
CrossRef citations to date
0
Altmetric
Research Article

A major rat faecal metabolite of ipronidazole

G. Weiss Departments of Animal Science Research and Chemical Research, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110, USA
,
N. Rose Departments of Animal Science Research and Chemical Research, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110, USA
,
P. Duke Departments of Animal Science Research and Chemical Research, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110, USA
&
T. H. Williams Departments of Animal Science Research and Chemical Research, Hoffmann-La Roche Inc., Nutley, New Jersey, 07110, USA
Pages 207-215 | Received 26 May 1980, Published online: 22 Sep 2008
 
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Abstract

1. A major water-soluble metabolite of ipronidazole (1-methyl-2-isopropyl-5-nitroimidazole) has been isolated from the faeces of bile-cannulated rats.

2. This metabolite has been identified by spectroscopic and chemical methods as 2,3-dihydro-2-(2-hydroxypropyl)-3-methyl-4-nitro-1H-imidazol-5-ol.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.