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Xenobiotica
the fate of foreign compounds in biological systems
Volume 13, 1983 - Issue 3
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Research Article

Factors affecting the sensitivity of X-ray films used for whole-body autoradiography

Pages 163-169 | Received 15 Oct 1982, Published online: 22 Sep 2008
 

Abstract

1. The sensitivities of five X-ray films commonly used for autoradiography of whole-body sections and thin-layer chromatograms were determined. The films tested were Kodak NS-2T, XAR-5, Industrex C, Agfa-Gevaert Osray M3 and CEAverken Singul-X.

2. The order of sensitivity, from greatest to least, was found to be NS-2T, Osray M3, XAR-5, Singul-X and Industrex C. Increases in sensitivity following extended development were demonstrated for Industrex C.

3. A literature review has revealed confusion in the use, in whole-body autoradiography, or various measures of autoradiographic response, which, in view of the simple relationship between radiographic optical density and absorbed dose, need not have arisen.

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