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1. Methods for the synthesis of drug conjugates with sulphuric acid have been reviewed.
2. Some analytical methods are presented for the analysis of sulphate conjugates.
3. The synthesis of several types of N, O and C β-D-glucuronides is reviewed. Different β-coupling reactions of protected glucuronides are presented.
4. Application of n.m.r. and mass spectrometry to the analysis of β-D-glucuronides is discussed.
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